Department of Genetic Engineering

The Human Genome Project is one of the best examples of Bioinformatics. This rapidly developing branch of biology is highly interdisciplinary, using concepts and techniques from informatics, statistics, mathematics, retrieval and analysis of data related to biological systems. The department strives to train human resource to take up the challenges of the post-genomics era.

About the Department

The Human Genome Project is one of the best examples of Bioinformatics. This rapidly developing branch of biology is highly interdisciplinary, using concepts and techniques from informatics, statistics, mathematics, retrieval and analysis of data related to biological systems. The department strives to train human resource to take up the challenges of the post-genomics era.

Genetic Engineering:

The world has come to realize the miracles of Genetic Engg., in agriculture - higher yield and better varieties of crops, in medicine - diagnostics and cures that were only a dream a few years back. It’s in the news. It’s everywhere. It is the backbone of biotechnology. The opportunities for a genetic engineer in clinical and applied genetics today and in the future are boundless. the department aims to produce genetic engineers who excel in the field of genomics and gene manipulation. Towards this end, the department has brought together state of the art laboratories and a highly experienced and dedicated team of faculty.

Vision

To create a strong teaching base in the department of Genetic engineering results from the direct manipulation of DNA using various technical methods to scale new heights in mainstream media; and to produce a useful or desirable characteristic in an organism and on a molecular level and may include additions, deletions, or targeted changes to the genome for the welfare of the general public.

Mission

  • To find cheap diagnostic setups for common diseases by molecular modeling methods.
  • To develop point of care in pharmaceutical companies using drug designing tools.
  • To contribute to the society using the unique competencies provided by the educational experiences of the Bioinformatics Engineers.

Academics

Under Graduate

The B. Tech. in Bioinformatics is a broad and flexible degree program. The curriculum provides knowledge in basics on the three important integral sub disciplines - biology, computer science and information technology and skills in applying vast amount of biological information in genomics, proteomics, drug designing, molecular medicine, forensic analysis, veterinary science and crop improvement. The course is designed to produce bioinformatics engineers to reach the frontier, which would help as a platform in seeking employment or in pursuing higher studies.

The B. Tech. program in Genetic Engineering comprises foundation courses in Biology and Engineering. Unique courses like Biology of Vectors, Recombinant DNA Technology, Genome Mapping, Gene Therapy, Microarray Technology and Stem Cell Biology are offered by experienced faculty.

Post Graduate

The M. Tech. in Bioinformatics is a broad and flexible degree program. The curriculum provides knowledge in basics on the three important integral sub disciplines - biology, computer science and information technology and skills in applying vast amount of biological information in genomics, proteomics, drug designing, molecular medicine, forensic analysis, crop improvement and veterinary science. The course is designed to produce bioinformatics engineers to reach the frontier in bioinformatics, which would help as a platform in seeking employment or in pursuing higher studies.

Bharath University is the only place in India where post graduate training in latest Genetic Engineering Technologies is provided at global standards. Specialization is offered in human genetics, medical genetics and plant genetic engineering.

Research Focus

Research activities help the faculty to intellectually stimulate the young minds. Research in the department is focused on drug designing and development, protein purification and proteomics. Faculty are involved in student projects, internally funded pilot projects, externally funded projects and multi-institutional collaborative projects with research institutions in India and abroad.

Board of Studies
Name Designation
Dr.P.B.Ramesh Babu, Professor & Head Chairman
Faculty Members
Dr.P.Krishnamoorthy, Professor Member
Dr. R. Deepa Member
Mr. R. Krishna Kumar Member
Ms. G.Subashini Member
External Members
Suresh Kumar Rayala,
Associate Professor, Department of Biotechnology, IIT, Chennai
Member
Academic Expert
Dr. K. Rajeshwari
Director, Bioklone Biotech Pvt Ltd.
Member
Industrial Expert

Infrastructure

Our bioinformatics lab is well equipped with 20 computers and having many online and offline softwares such as Chemsketch, Arguslab and docking tools such as Autodock and Patchdock.

Molecular modelling lab has been helpful to students to identify the properties of chemical compounds are directly related to the ways in which atoms are bonded together into molecules. Students have the opportunity to apply their knowledge by constructing simple ball-and stick models for some common molecules. The models should help them understanding of electron arrangements in molecules and the resulting shapes of the molecules. They can investigate a number of small molecules containing carbon, nitrogen, oxygen and hydrogen, as well as a few molecules containing fluorine, chlorine, or sulfur.

PROGRAMS OFFERED
Curriculum and Syllabus
Undergraduate Programmes (4 Years)
B.Tech. - Genetic Engineering
Postgraduate Programmes (2 Years)
M. Tech - Computational Biology

Awards and Achievements of Faculty Members

  • Dr.T.Jayalakshmi - Awarded as Best teaching staff in the year 2012 at Bharath University, Chennai
  • Dr.P.Rajasulochana - Awarded as Best teaching staff in the year 2014 at Bharath University, Chennai
Awards and Achievements of Students
Name of the Faculty Activity Position Awarded by
Shri Vishalini R Classical dance(solo) II Women’s day celebration
Ram Kumar N Poster Presentation I National conference on Bio Engineering
Nismabi A .N Drawing II Women’s day celebration
Revathy.G Group dance II Women’s day celebration
Durgalaxshmi.C Debate II Women’s day celebration
S.Pavithra Group dance II Women’s day celebration

Research Activities

  • Scopus Indexed Publications - 120
  • Peer Reviewed Publications - 42
  • Conference Publications - 30
  • No. of citations above ten - 20
  • No. of MoU’s Signed - 01

Completed research projects:
S.No Topic Funding agency Guide Duration Status
1 Identification and evaluation of Gene expression profiles in inflammatory lung diseases ClonegenPvt ltd Dr. P. Rajasulochana 1 year Major
2 In silico analysis of inflammatory Genes associated with Asthma. ImmunogenPvt ltd Dr. P. B. Ramesh Babu 2 year Minor
3 Genomics of Nonmicrobial mediated inflammatory Diseases TechbioPvt ltd Dr. P. B. Ramesh Babu 1 yaer Major
4 Identification of drug target sites on food pathogens using bioinformatics tools HDR Pvt ltd Dr. P. Rajasulochana 2 year Major
5 Evolutionary studies on Mora eel with in-silico drug designing BiochemPvt ltd Dr. T. Jayalakshmi 1 Year Minor

Ongoing-Research Projects
S.No Topic Funding agency Amount Principle Investigator Duration
1 Research Studies on Marine Algae (Kappaphycus Red Algae in view of Pharmacological applications BIHER 3.5 lacs Dr.P.Rajasulochana 3 years
2 Identification and Characterization and structural elucidation of Keratinases producing fungi and their applications in pharmaceutical industries BIHER 1 lacs Dr.P.B.Ramesh Babu 2 years
3 Evaluation of novel chemopreventive agents Sulforamate, Oxomate and Brassinin as anticancer and anti-inflammatory agents BIHER 6 lacs Dr.P.Rajasulochana 3 years
4 Evaluation of protein components of inflammation and immunity in airway epithelial cells BIHER 1.5 lacs Dr.P.B.Ramesh Babu 2 years
5 Evaluation of Research studies on marine Red Algae (Kappaphycus Alvarezii) as Biofertiliser for agricultural applications BIHER 3 lacs Dr.P.B.Ramesh Babu 2 years